Dental Pulp Stem Cell: A Promising Tool in Forensic Odontology
Keywords:
Forensic Odontology; Forensic Den????stry; Stem Cells; Dental Pulp Stem CellsAbstract
Forensic odontology, also known as forensic den????stry, is a specialized field within den????stry that deals with the applica????on of
dental science in medico-legal inves????ga????ons, iden????fying accidental human remains during mass disasters, iden????fying
vic????ms from the site of crime scene. Most of human body parts perish a????er death, but tooth is one such organ which is
incredibly resilient, preserving DNA well even in extreme condi????ons that may destroy other human body parts. Therefore,
they serve as an excellent source of gene????c material for iden????fying individuals in forensic cases. Stem cells, with their ability
to develop into different cell types, have various applica????ons in forensic inves????ga????ons, including iden????fica????on,
reconstruc????on, and age es????ma????on. Dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous teeth
(SHED) are par????cularly valuable in forensic iden????fica????on. Amongst other methods used in Forensic odontology the use of
DPSCs gives us significant results and aid in an accurate finding. The ar????cle intends to discuss the basis of DPSCs, its sources
and methods of isola????on, applica????ons, accuracy of DPSCs through case study and its limita????ons.